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Novel and Diverse Research Organization Structures 

We should design research institutions to support the particular kinds of research they need to house, not fit every square peg into the same round hole.

R&D Gaps (1)

This is more of a meta-bottleneck. But scientists are spending a lot of time not doing science, and the institutional structures in which they work are often set up with incentive structures that hinder certain kinds of outcomes, like more coordinated research.