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Index: #29

Manual and Laborious Nature of Chemical Synthesis

Chemical synthesis remains largely manual, limiting throughput and reproducibility. The field requires robust automation to accelerate discovery and production of new molecules.

Foundational Capabilities (7)

Implement a “chemputer” system to automate chemical synthesis processes, reducing human intervention and increasing reproducibility.
Develop and utilize a better set of standardized building blocks to enable modular synthesis, making the assembly of complex molecules more efficient and scalable.
Direct long DNA synthesis could still be cheaper.  Biosecurity consideration: implementation should be governed by security measures such as: • Trustless DNA synthesis screening • Hardware lock for DNA synthesizer See these capabilities under the “Risks of Malicious Bioengineering” bottleneck.
Fast on-demand complex peptide manufacturing
Synthesize massive biopolymer libraries according to the statistics of a generative model
Physics based control across the cell membrane of DNA synthesis inside the cell as a route to maximize “bandwidth across the cell membrane”