Gene Expression Control of Cellular Transplants in the Brain
Technologies to control gene expression in single neurons post-transplantation. Light-based or acoustic methods could offer precision for neuro-activation to enable axonal guidance and integration and enable cellular transplantation for neuroregeneration, circuitry reconstruction etc.
Resources (3)
Acoustically targeted chemogenetics for the non-invasive control of neural circuits
Research and Reviews
Near-infrared optogenetic pair for protein regulation and spectral multiplexing
Research and Reviews
R&D Gaps (1)
Large portions of the living human brain are difficult to observe and modulate with current technologies. Safer, noninvasive, or minimally invasive methods are needed to capture real-time brain state information.
One funding program dedicated to making advancements in this space is that of ARIA (...