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Physiology and Medicine

Improved Diagnostics

Diagnostic tools for the top 10 hard to diagnose diseases could have a significant impact on patients and the healthcare ecosystem. Diagnostics as an industry is in a state of market failure. Many disorders remain challenging to diagnose, impacting patient outcomes and burdening the healthcare system. Monitoring the epigenome can enable the identification of exposures to infectious disease and reveal exposure to threat agents.

Resources (3)

Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs
Research and Reviews
Update on PCOS: Consequences, Challenges, and Guiding Treatment
Research and Reviews
DARPA: Reading the Body’s History of Threat Exposure
Funding Program

R&D Gaps (1)

Clinical Trials are Inefficient, Slow and Scarce

Physiology and Medicine
Clinical trial designs are often inefficient, resulting in high costs, lengthy timelines, and suboptimal patient outcomes. Innovative trial designs and decision-support tools are required to streamline the clinical evaluation process and accelerate therapeutic development.
Physiology and Medicine
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