In-Vivo Optical Transparency of Brain Tissue
Develop techniques that render brain tissue optically transparent in vivo, allowing deeper and higher-resolution imaging of neural networks without invasive sectioning.
Resources (1)
In Vivo Optical Clearing of Mammalian Brain
Technology Seed
R&D Gaps (1)
We Can’t Take High-Resolution Movies of or Intervene in Brain Computation at the Single Neuron Level
Capturing the dynamics of large brain networks at single-neuron resolution in vivo is extremely challenging. Advanced imaging methods that record fast, high-resolution activity without destructive intervention are required to unravel the complex interplay of neuronal circuits in real time.