Novel Fast-Scanning Microscopy of Brain Cortex
Develop innovative microscopy techniques that enable rapid, high-resolution imaging of neuronal networks in vivo at single–neuron resolution (e.g., Light Beads Microscopy)
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We Can’t Take High-Resolution Movies of or Intervene in Brain Computation at the Single Neuron Level
Capturing the dynamics of large brain networks at single-neuron resolution in vivo is extremely challenging. Advanced imaging methods that record fast, high-resolution activity without destructive intervention are required to unravel the complex interplay of neuronal circuits in real time.