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Biosecurity

Novel Vaccine Technologies

Security Risk
Develop innovative vaccine platforms that can adapt to or be robust to rapidly mutating viruses (e.g., influenza, HIV, coronaviruses) using methods such as mosaic nanoparticles and mRNA cocktails. Safety and security considerations: https://www.sciencedirect.com/science/article/pii/S0264410X21001717 

Resources (6)

Cenitvax
Company
HelixNano
Company
PanV
Company
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
Research and Reviews
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
Research and Reviews
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
Initiative

R&D Gaps (1)

Microbes Quickly Out-Evolve Our Defenses

Biosecurity
Pathogenic microbes evolve quickly, and bad actors may exploit biotechnology for harmful purposes. Our current defenses struggle to keep pace with these evolving threats.
Biosecurity
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