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Synthetic Biology
Index: #31

Limited Microbial Hosts/Chassis Organisms

Scientists are constrained to a small number of microbial hosts for bioproduction, limiting the diversity and efficiency of engineered biological systems. Expanding the repertoire of microbial hosts could unlock novel biochemical pathways, enabling the production of a wider array of biomolecules and improving the efficiency of biosynthetic processes. It is important to address any biosafety and biosecurity risks associated with developing such technologies.

Foundational Capabilities (1)

New Microbial Chassis

Create platforms that simplify the process of identifying and adapting new microbial hosts, providing recipes for their use in synthetic biology applications. This could take advantage of biocontainment approaches to enhance safety.
  • Cultivarium: Access the genetic potential of the biosphere
    FRO
  • Adam Guss: Taming Wild Microbes for the Bioeconomy
    Initiative